Dnp-Pro-Cha-Gly-Cys(Me)-His-Ala-Lys(Nma)-NH₂

Product overview
Catalog Number
PPH07-146
Sequence
Dnp-Pro-Cha-Gly-Cys(Me)-His-Ala-Lys(NMa)-NH2
Target
Substrate for Collagenase; Substrate for MMP-1 and MMP-9
Description
2,4-Dinitrophenyl-L-Prolyl-L-Cyclohexylalanyl-Glycyl-S-Methyl-L-Cysteinyl-L-Histidyl-L-Alanyl-N-epsilon-Methylanthranoyl-L-Lysine Amide (M.W. 1077.24) C49H68N14O12S Substrate for Collagenase. Dnp-P-Cha-G-Cys(Me)-HA-K(Nma)-NH2 is a fluorogenic substrate for matrix metalloproteinase-1 (MMP-1) and MMP-9.1 Upon cleavage by MMP-1 or MMP-9, N-methylanthranilic acid (Nma) is unquenched and its fluorescence can be used to quantify MMP activity. Nma displays excitation/emission spectra of 340/440 nm, respectively.
Category
Enzyme Inhibitors and Substrates, Catalog peptides
Product Properties
Quantity

2,5mg, 5mg
Storage

Shipped at 4°C. Store at -20°C for one year.
Purity

> 95%
Source

Synthetic
Forma appearance

Lyophilized powder
  • For research use only
  • Not for use in diagnostic procedures

€157,00 – €275,00 Tax excluded
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