E-64 (0.5 mg vial)

Product overview
Catalog Number
PPH07-160
Sequence
L-trans-Epoxysuccinyl-Leu-agmatine
Target
Inhibitor for Thiol Proteases; Calpain inhibitor
Description
(L-3-trans-Carboxyoxiran-2-Carbonyl)-L-Leucylagmatine (M.W. 357.41) C15H27N5O5 [66701-25-5] Synthetic Product Inhibitor for Thiol Proteases. E-64 is an epoxide which can irreversibly inhibit a wide range of cysteine peptidases. The compound was first isolated and identified from Aspergillus japonicus in 1978. It has since been shown to inhibit many cysteine peptidases such as papain, cathepsin B, cathepsin L, calpain and staphopain. The low toxic effects of the inhibitor, in addition to its effective mechanism of action, makes E-64 a potential template for drugs to treat diseases where high levels of a cysteine proteases are the primary cause.
Category
Enzyme Inhibitors and Substrates, Catalog peptides
Product Properties
Quantity

1mg
Storage

Shipped at 4°C. Store at -20°C for one year.
Purity

> 95%
Source

Synthetic
Forma appearance

Lyophilized powder
Price

€29,00
  • For research use only
  • Not for use in diagnostic procedures

€29,00 Tax excluded
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