E-64-c (5 mg vial)

Product overview
Catalog Number
PPH07-161
Sequence
(L-3-trans-Carboxyoxirane-2-Carbonyl)-L-Leucine (3-Methylbutyl)Amide
Target
Inhibitor for Thiol Protease (Cathepsin B/H/L); Calpain inhibitor
Description
E-64-c is an effective synthetic calpain inhibitor composed from E-64 (sc-201276), which also inhibits cathepsin B, cathepsin H, and cathepsin L (cysteine proteases). The compound has been demonstrated to form a complex with papain by binding via a thioether covalent bond. Studies indicate that E-64-c, also known as Ep-475, is a more potent inhibitor of cathepsins B and L compared to E-64. Mouse lymphosarcoma LS studies show that Ep-475 decreases the effects of cyclophosphamide. (L-3-trans-Carboxyoxirane-2-Carbonyl)-L-Leucine (3-Methylbutyl)Amide (M.W. 314.38) C15H26N2O5 [76684-89-4] Synthetic Product Inhibitor for Thiol Protease (Cathepsin B/H/L and Calpain)
Category
Enzyme Inhibitors and Substrates, Catalog peptides
Product Properties
Quantity

1mg
Storage

Shipped at 4°C. Store at -20°C for one year.
Purity

> 95%
Source

Synthetic
Forma appearance

Lyophilized powder
Price

€104,00
  • For research use only
  • Not for use in diagnostic procedures

€104,00 Tax excluded
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