Cyclosporin-A

Product overview
Catalog Number
PPH08-0310
Sequence
PMATZTZNYRCHOR-CGLBZJNRSA-N. C62H111N11O12
Target
mmunosuppressant drug
Description
Cyclosporin A is an immunosuppressant drug that binds cyclophilin D, inhibiting the phosphatase activity of calcineurin in T cells (IC50 = 5 nM). It blocks the transcription of genes involved in T cell activation by interfering with the calcineurin-driven nuclear import of the transcription factor NFAT. Because of its powerful immunosuppressant activity, cyclosporin A has long been used for the prevention of transplant rejection.
Category
Catalog peptides, Biologically Active Peptides
Product Properties
Quantity

1g, 4g, 100g
Storage

Shipped at 4°C. Store at -20°C for one year.
Purity

> 95%
Source

Synthetic
Forma appearance

Lyophilized powder
  • For research use only
  • Not for use in diagnostic procedures

€30,00 – €1.180,00 Tax excluded
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