[Arg8]-Vasopressin

Product overview
Catalog Number
PPH08-0140
Sequence
H-[Cys-Tyr-Phe-Gln-Asn-Cys]-Pro-Arg-Gly-NH2
Target
Peptide Antidiuretic Hormone Originating from Hypothalamus; Plays Role in Osmolalit
Description
Argipressin (Synonyms: AVP, [Arg8]-Vasopressin) is a peptide hormone with vasoconstrictive and antidiuretic activities that binds to the vascular arginine vasopressin receptor, V1, with Kd values of 1.31 and 1.44 nM in A7r5 rat aortic smooth muscle cells and neonatal rat cardiomyocytes, respectively.1,2 It also stimulates the intracellular release of calcium in A7r5 cells (EC50 = 5 nM).3 In rat models, argipressin induces hypertension and tachycardia when injected into the lateral septal nuclei at a dose of 100-400 ng and increases heart rate and mean arterial pressure (MAP) when injected into the medial amygdaloid body at a dose of 150-600 ng.4,5
Category
Catalog peptides, Biologically Active Peptides
Product Properties
Quantity

1mg, 5mg
Storage

Shipped at 4°C. Store at -20°C for one year.
Purity

> 95%
Source

Synthetic
Forma appearance

Lyophilized powder
  • For research use only
  • Not for use in diagnostic procedures

€50,00 – €260,00 Tax excluded
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