Cyclorasin 9A54

Product overview
Catalog Number
PPH08-0303
Sequence
cyclo(Arg-Phe(3,4-Di-F)-D-Nle-Gln-Trp-Tle-D-Val-Arg-Arg-Arg-2-D-Nal)
Target
Weak anti-proliferative activity against lung cancer cells.
Description
Cyclorasin 9A54 . M.W. 1645.0) C79H115N25O12F2. Trifluoroacetate salt. hits 9A inhibited the Ras-Raf interaction with IC50 values of 0.65 and 1.0 μM. Gratifyingly, hits 9A contained additional Trp and/or Arg residues in the X2-X5 region, were cell permeable, and exhibited weak anti-proliferative activity against lung cancer cells.
Category
Product Properties
Quantity

1mg, 5mg

Storage

Shipped at 4°C. Store at -20°C for one year.

Purity

> 95%

Source

Synthetic

Forma appearance

Lyophilized powder

  • For research use only
  • Not for use in diagnostic procedures

462,001.906,00 Tax excluded

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