Guanylin

Product overview

Description: Guanylin is a 15 amino acid polypeptide that is secreted by goblet cells in the colon. Guanylin acts as an agonist of the guanylyl cyclase receptor GC-C and regulates electrolyte and water transport in intestinal and renal epithelia. Upon receptor binding, guanylin increases the intracellular concentration of cGMP, induces chloride secretion and decreases intestinal fluid absorption, ultimately causing diarrhoea. The peptide stimulates the enzyme through the same receptor binding region as the heat-stable enterotoxins. (Disulfide bonds between Cys4-Cys12 and Cys7-Cys15) (M.W. 1515.7) C60H90N16O22S4 Guanylate Cyclase C Activator.

Category

Product Properties

Quantity	1mg
Storage	Shipped at 4°C. Store at -20°C for one year.
Purity	> 95%
Source	Synthetic
Forma appearance	Lyophilized powder
Price	€120,00

€120,00 Tax excluded

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