Hepcidin (Crocodile)

Product overview
Catalog Number
PPH08-0579
Sequence
H-Asn-Ser-His-Phe-Pro-Ile-Cys-Ser-Tyr-Cys-Cys-Asn-Cys-Cys-Arg-Asn-Lys-Gly-Cys-Gly-Leu-Cys-Cys-Arg-Thr-OH
Target
Iron Homestasis Regulator
Description
Hepcidin, a cysteine-rich cationic antibacterial peptide, plays an important role in human defense against pathogen infection. However, its role in reptile immune response and whether it is involved in antibacterial immune have not yet been proven. In order to study the antibacterial activity of Crocodylus siamensis hepcidin (Cshepc), a common reptile which lives in topic region of Southeast Asia, a cDNA sequence of Cshepc was cloned, which included an open reading frame (ORF) of 300bp encoding a 99 amino acid preprohepcidin. Cshepc has eight cysteines formed four conserved disulfide bridges, similarly to that of human's. Sequence analysis showed that Cshepc mature peptide was more conserved than that of preprohepcidin. Iron Homestasis Regulator. Disulfide Bonds: Cys7-Cys23, Cys10-Cys13, Cys11-; Cys19, and Cys14-Cys22.
Category
Catalog peptides, Biologically Active Peptides
Product Properties
Quantity

1mg, 5mg
Storage

Shipped at 4°C. Store at -20°C for one year.
Purity

> 95%
Source

Synthetic
Forma appearance

Lyophilized powder
  • For research use only
  • Not for use in diagnostic procedures

€729,00 – €2.976,00 Tax excluded
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