HsTX1

Product overview
Catalog Number
PPH08-0583
Sequence
H-Ala-Ser-Cys-Arg-Thr-Pro-Lys-Asp-Cys-Ala-Asp-Pro-Cys-Arg-Lys-Glu-Thr-Gly-Cys-Pro-Tyr-Gly-Lys-Cys-Met-Asn-Arg-Lys-Cys-Lys-Cys-Asn-Arg-Cys-NH2
Target
Kv1.3 Channel Blocker (IC50 ~ 12pM), A peptide toxin with a sequence derived from the scorpion, Heterometrus spinnifer, which blocks the Kv1.3 potassium channel.
Description
HsTx1 is a toxin from the venom of the scorpion Heterometrus spinifer. HsTx1 is a very potent inhibitor of the rat Kv1.3 voltage-gated potassium channel. HsTx-1 is a member of the a-KTx6 family of scorpion toxins active on voltage-gated Kv1.3 channels (Kd close to 10 pM). HsTx-1 is also very active on Kv1.1 channels (IC50 around 7 nM). It is however inactive on apamin-sensitive SK channels. It is one of the most potent toxins active on Kv1.3 channel. A 34 amino-acids peptide with 4 disulfide bridges , synthetic, initially isolated from the venom of the Giant forest scorpion Heterometrus spinifer.
Category
Catalog peptides, Biologically Active Peptides
Product Properties
Quantity

1mg, 5mg
Storage

Shipped at 4°C. Store at -20°C for one year.
Purity

> 95%
Source

Synthetic
Forma appearance

Lyophilized powder
  • For research use only
  • Not for use in diagnostic procedures

€729,00 – €2.976,00 Tax excluded
Contact us to request price here
Register to buy peptides
Contact us