Insulin Chicago (Human)

Product overview
Catalog Number
PPH08-0645
Sequence
-
Target
Is a variant in which valine at position A3 is substituted by leucine.
Description
Point mutation in the human insulin gene giving rise to a structurally abnormal insulin (insulin Chicago) Both insulin gene alleles of a diabetic patient with a mutant insulin were cloned in a lambda vector and their nucleotide sequences were determined. Nucleotide sequence analysis revealed, in one allele, a C (cytidylate) to G (guanylate) transversion in the codon for phenylalanine at position 25 of the insulin B-chain. This point mutation leads to the substitution of a leucine for phenylalanine accompanied by the loss of a restriction endonuclease Mboll recognition site and the creation of a new Rsal cleavage site at this position.
Category
Catalog peptides, Biologically Active Peptides
Product Properties
Quantity

50µg, 100µg, 500µg
Storage

Shipped at 4°C. Store at -20°C for one year.
Purity

> 95%
Source

Synthetic
Forma appearance

Lyophilized powder
  • For research use only
  • Not for use in diagnostic procedures

€330,00 – €1.980,00 Tax excluded
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