Neuromedin U (Rat) (0.5 mg vial)
Product overview
- Catalog Number
- PPH08-0787
- Sequence
- Tyr-Lys-Val-Asn-Glu-Tyr-Gln-Gly-Pro-Val-Ala-Pro-Ser-Gly-Gly-Phe-Phe-Leu-Phe-Arg-Pro-Arg-Asn-NH2
- Target
- Food Intake Suppressor
- Description
- NM-U. Neuromedin U (NMU), was identified as a single entity, consisting of 23 amino acid residues (NMU-23) because of lack of the double basic site (Gly-Gly substitution for Arg-Arg). In addition to its role in smooth muscle contraction, NMU exerts some other biological activities such as increase of blood pressure, induction of ACTH release, etc. However, the specific receptor for NMU has long been unidentified. NMU itself is present in the brain as well as in the gut. Applying the recently developed technique of using the so-ca lied orphan G-protein coupled receptors, NMU has been reported to be a ligand of two structurally related receptors by several groups Endogenous peptide regulating blood pressure, ion transport in the gut, mesenteric blood flow and adrenocortical function. Also decreases food intake and body weight, increases body temperature and heat production, and inhibits gastric acid secretion via the CRH system following central administration in vivo. The kit is a competitive inhibition enzyme immunoassay technique for the in vitro quantitative measurement of NMU in rat serum, plasma, tissue homogenates or other biological fluids. May induce uterine smooth muscle contraction and selective vasoconstriction. Stimulates muscle contractions of specific regions of the gastrointestinal tract. In rat, NMU stimulates contractions of stomach circular muscle.
Category
Product Properties
| Quantity | 1mg |
|---|---|
| Storage | Shipped at 4°C. Store at -20°C for one year. |
| Purity | > 95% |
| Source | Synthetic |
| Forma appearance | Lyophilized powder |
| Price | €248,00 |
- For research use only
- Not for use in diagnostic procedures
€248,00 Tax excluded
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