HIV is divided into two subtypes, HIV-1 and HIV-2, and the majority of AIDS patients in the world are infected by HIV-1.
HIV - 1, Envelope Glycoprotein
HIV-1 is an RNA virus whose genome is composed of about 9,200bp. Its genome encodes three major structural peptides Gag, Pol and Env, two regulatory peptides Tat and Rev, and four auxiliary peptides Nef, Vpr, Vif and Vpu. Besides, HIV-1 related peptides also include nucleocapsid peptides NCp7, GP120, GP41 and so on. At present, the drug designs for these peptides has become one of the hot topics in AIDS research. Peptidepharma had identified several GP120 and gp41 peptide fragments that can be used for diagnostic purposes.
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