ω-Conotoxin SVIB (0.5 mg vial)

Product overview
Catalog Number
PPH08-0845
Sequence
Cys-Lys-Leu-Lys-Gly-Gln-Ser-Cys-Arg-Lys-Thr-Ser-Tyr-Asp-Cys-Cys-Ser-Gly-Ser-Cys-Gly-Arg-Ser-Gly-Lys-Cys-NH2
Target
A synthetic cone snail toxin. Na-type Ca2+ Channel Blocker
Description
ω-Conotoxin SVIB, an analogue of ω-conotoxin GVIA, is a peptide toxin originally isolated from Conus striatus venom. It is a potent blocker of N-type voltage-gated Ca2+ channels. It has an analgesic effect and is being used as a potential drug for the treatment of chronic and neuropathic pain models. ω-Conotoxins are disulfide-rich peptides comprises 24–31 amino acids, isolated from the venom of marine predatory cone snails. These conotoxins have a high content of basic amino acid residue and a common cysteine scaffold that stabilizes the four-loop framework. (Marine Snail, Conus striatus) (Disulfide bonds between Cys1-Cys16,Cys8-Cys20, and Cys15-Cys26) (M.W. 2739.1) C105H176N38O36S6 [150433-82-2]
Category
Product Properties
Quantity

1mg

Storage

Shipped at 4°C. Store at -20°C for one year.

Purity

> 95%

Source

Synthetic

Forma appearance

Lyophilized powder

Price

€382,00

  • For research use only
  • Not for use in diagnostic procedures

382,00 Tax excluded

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