Amyloid beta (A4) Precursor Protein Human Recombinant

Product overview
Catalog Number
PPH08-0125
Sequence
-
Target
Cell surface receptor and transmembrane precursor protein which is cleaved by secretases to form a number of peptides. ELISA (EIA), Western Blot (WB), Immunofluorescence (IF)
Description
Amyloid beta A4 protein (APP) functions as a cell surface receptor and transmembrane precursor protein which is cleaved by secretases to form a number of peptides. A number of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to stimulate transcriptional activation, whereas others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. APP gene mutations are implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy).
Category
Catalog peptides, Biologically Active Peptides
Product Properties
Quantity

5µg, 20µg, 1000µg
Storage

Shipped at 4°C. Store at -20°C for one year.
Purity

> 95%
Source

Synthetic
Forma appearance

Lyophilized powder
  • For research use only
  • Not for use in diagnostic procedures

€30,00 – €2.680,00 Tax excluded
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