Angiotensin II (Human) (0.5 mg vial)

Product overview
Catalog Number
PPH08-0055
Sequence
Asp-Arg-Val-Tyr-Ile-His-Pro-Phe
Target
Angiotensin II (angII) human has been used to study its effect on interleukin-1β–mediated islet inflammation and β-cell dysfunction. It has been used to determine if angII activates specific calcineurin-dependent NFAT (nuclear factor of activated T-cells)
Description
Angiotensin II is a peptide hormone known best as a vasoconstrictor with central roles in chronic hypertension, heart failure, and stroke. It is an octapeptide typically generated by the removal of two residues from angiotensin I by angiotensin-converting enzyme (ACE). Angiotensin II is a ligand for at least two distinct receptors, AT1 and AT2, each evoking distinct signaling pathways and physiological responses. The development of antagonists for specific angiotensin II receptor subtypes represents a valuable alternative to ACE inhibitors.
Category
Product Properties
Quantity

1mg

Storage

Shipped at 4°C. Store at -20°C for one year.

Purity

> 95%

Source

Synthetic

Forma appearance

Lyophilized powder

Price

€18,00

  • For research use only
  • Not for use in diagnostic procedures

18,00 Tax excluded

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