Angiotensin II (Human)
Product overview
- Catalog Number
- PPH08-0054
- Sequence
- Asp-Arg-Val-Tyr-Ile-His-Pro-Phe • AcOH • 4H2O
- Target
- Angiotensin II (angII) human has been used to study its effect on interleukin-1β–mediated islet inflammation and β-cell dysfunction. It has been used to determine if angII activates specific calcineurin-dependent NFAT (nuclear factor of activated T-cells)
- Description
- Angiotensin II is a peptide hormone known best as a vasoconstrictor with central roles in chronic hypertension, heart failure, and stroke. It is an octapeptide typically generated by the removal of two residues from angiotensin I by angiotensin-converting enzyme (ACE). Angiotensin II is a ligand for at least two distinct receptors, AT1 and AT2, each evoking distinct signaling pathways and physiological responses. The development of antagonists for specific angiotensin II receptor subtypes represents a valuable alternative to ACE inhibitors.
Category
Product Properties
| Quantity | 25mg |
|---|---|
| Storage | Shipped at 4°C. Store at -20°C for one year. |
| Purity | > 95% |
| Source | Synthetic |
| Forma appearance | Lyophilized powder |
| Price | €490.00 |
- For research use only
- Not for use in diagnostic procedures
€490,00 Tax excluded
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