Antipain (Synthetic)

Product overview
Catalog Number
PPH08-0145
Sequence
(S)-1-Carboxy-2-phenylethyl]-carbamoyl-RVR-H
Target
Synthetic Product Inhibitor for Trypsin, u-PA, Papain, and Cathepsin A/B
Description
Antipain is an oligopeptide that is isolated from actinomycetes and used in biochemical research as a protease inhibitor of trypsin and papain. It was discovered in 1972 and was the first natural peptide found that contained an ureylene group. It has been crystallised in complexes with carboxypeptidase, which is obtained from wheat, and Leishmania major oligopeptidase B. In both cases, the backbone carbonyl of the terminal arginine of antipain forms a covalent bond to the active site serine in the protease. In oncology, pain control is an ongoing problem. An important obstacle to controlling cancer pain is related to the patient. A recent research article indicated that antipain Y is a new type of anti-pain analog, which can inhibit the release of neurotransmitter in rat dorsal root ganglion neurons.
Category
Catalog peptides, Biologically Active Peptides
Product Properties
Quantity

25mg, 100mg
Storage

Shipped at 4°C. Store at -20°C for one year.
Purity

> 95%
Source

Synthetic
Forma appearance

Lyophilized powder
  • For research use only
  • Not for use in diagnostic procedures

€109,00 – €318,00 Tax excluded
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