Big Endothelin-2 (Human, 1-37) (0.1mg vial)
Product overview
- Catalog Number
- PPH08-0200
- Sequence
- Cys– Ser – Cys – Ser – Ser – Trp – Leu – Asp – Lys – Glu – Cys – Val – Tyr – Phe – Cys – His – Leu – Asp – Ile – Ile – Trp – Val – Asn – Thr – Pro – Glu – Gln – Thr – Ala – Pro – Tyr – Gly – Leu – Gly – Asn – Pro – Pro
- Target
- Big Endothelin-2 is the precursor to the vasoconstricting peptide Endothelin-2 (ET-2). It is hydrolyzed by endothelin converting enzyme (ECE)
- Description
- Endothelins (ET) show potent constrictor activity in vascular and non-vascular smooth muscle. This family of 21-amino acid peptides exists in at least three isoforms, ET-1, ET-2, and ET-3, and is produced in endothelial and epithelial cells. ET's can mediate biological effects in cells and tissues, and have been shown to bind to an ET receptor in the lung, kidney, heart and liver. Sequence (linear): Cys-Ser-Cys-Ser-Ser-Trp-Leu-Asp-Lys-Glu-Cys-Val-Tyr-Phe-Cys-His-Leu-Asp-Ile-Ile-Trp-Val-Asn-Thr-Pro-Glu-Gln-Thr-Ala-Pro-Tyr-Gly-Leu-Gly-Asn-Pro-Pro , Storage and Stability: , Lyophilized powder may be stored at 4°C for short-term only. Stable for 12 months at -20°C. Reconstitute to nominal volume (see reconstitution instructions for peptides) and store at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer. ,
Category
Product Properties
| Quantity | 1mg |
|---|---|
| Storage | Shipped at 4°C. Store at -20°C for one year. |
| Purity | > 95% |
| Source | Synthetic |
| Forma appearance | Lyophilized powder |
| Price | €248.00 |
- For research use only
- Not for use in diagnostic procedures
€248,00 Tax excluded
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