Candidalysin (0.5 mg vial)

Product overview
Catalog Number
PPH08-0312
Sequence
Ser-Ile-Ile-Gly-Ile-Ile-Met-Gly-Ile-Leu-Gly-Asn-Ile-Pro-Gln-Val-Ile-Gln-Ile-Ile-Met-Ser-Ile-Val-Lys-Ala-Phe-Lys-Gly-Asn-Lys
Target
Fungal Cytolytic Peptide Toxin
Description
Candidalysin is a cytolytic 31-amino acid α-helical amphipathic peptide toxin found in the opportunistic pathogen Candida albicans that activates epithelial cells. As such, Candidalysin is a rare fungal example of a classical virulence factor. Hyphal morphogenesis in C. albicans is associated with damage to host epithelial cells; during this process Candidalysin is released. Candidalysin promotes damage of oral epithelial cells by inducing lactate dehydrogenase release and calcium ion influx. It is unique in the fact that it is the first peptide toxin to be identified in any human fungal pathogen.
Category
Catalog peptides, Biologically Active Peptides
Product Properties
Quantity

1mg
Storage

Shipped at 4°C. Store at -20°C for one year.
Purity

> 95%
Source

Synthetic
Forma appearance

Lyophilized powder
Price

€260.00
  • For research use only
  • Not for use in diagnostic procedures

€260,00 Tax excluded
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