Chemotactic Peptide

Product overview
Catalog Number
PPH08-0247
Sequence
For-Met-Leu-Phe
Target
Receptor Site on Human Leukocyte
Description
N-formyl-L-methionyl-L-leucyl-L-phenylalanine. Is a synthetic peptide that acts as an agonist at formyl peptide receptors (FPRs; Ki = 0.8 pM), which are mainly localized on polymorphonuclear and mononuclear phagocytes.1 Activation of FPRs by fMLF leads to cellular activation, which is characterized by cellular polarization, chemotaxis, and release of proteolytic enzymes.2 fMLF induces contractions in isolated guinea pig jejunum (EC50 = 11 nM), proximal colon (EC50 = 3.5 nM), and distal colon (EC50 = 2.2 nM).3 In vitro, fMLF induces neurotransmitter release from enteric motor neurons.
Category
Catalog peptides, Biologically Active Peptides
Product Properties
Quantity

25mg, 100mg
Storage

Shipped at 4°C. Store at -20°C for one year.
Purity

> 95%
Source

Synthetic
Forma appearance

Lyophilized powder
  • For research use only
  • Not for use in diagnostic procedures

€86,00 – €291,00 Tax excluded
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