Clickable-TAT Azide (49-57)

Product overview
Catalog Number
PPH08-0296
Sequence
5-azido-pentanoyl-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-NH2
Target
Modified HIV TAT Sequence 49-57 for Click Chemistry
Description
TFA salt 5-azido-pentanoyl-RKKRRQRRR-NH2 C58H114N34O14 MW: 1511.77 HIV TAT sequence 49-57 This arginine-rich TAT peptide penetrates plasma membrane directly, but not through endocytosis. TAT (49-57) is modified with 5-Azido-pentanoic acid for click chemistry. The azido group can react with alkyne containing molecules in the presence of Cu/CuSO4 yielding a conjugate crosslinked by a triazole moiety. The reaction can be applied for the conjugation of TAT to various molecules include oligonucleotides to facilitate cell penetration for therapeutic applications.
Category
Product Properties
Quantity

1mg, 5mg

Storage

Shipped at 4°C. Store at -20°C for one year.

Purity

> 95%

Source

Synthetic

Forma appearance

Lyophilized powder

  • For research use only
  • Not for use in diagnostic procedures

221,00943,00 Tax excluded

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