Cys(Npys)-TAT (49-57), FAM-labeled

Product overview
Catalog Number
PPH08-0332
Sequence
H-Cys(Npys)-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-Lys(FAM)-NH2
Target
Cys- Activated and FAM-labeled TAT for Cargo Conjunction
Description
Cys(Npys)-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-Lys(FAM)-NH2 (M.W. 2082.42) C88H136N36O20S2 FAM Labeled, Cys-Activated TAT a cell penetrating peptide derived from the HIV-1 tat protein transduction domain (PTD) with fluorescent label, has been shown to promote the entry of nucleic acids into several cell types. This peptide corresponds to the protein transduction domain of the TAT protein and is synthesized with an activated cysteine residue C(Npys), wherein Npys is 3-Nitro-2-pyridinesulfenyl group and is used for activating S of cysteine and for rapid reaction when a thiol group is introduced. This is synthesized with C(Npys) at the N-terminus for applications requiring specific conjugation reactions and has a fluorophore labeled with FAM having Abs/Em=494/518 nm. This kind of modification has been used to render this peptide as a cell penetrating and carrier peptide applicable in conjugation studies.
Category
Catalog peptides, Biologically Active Peptides
Product Properties
Quantity

1mg, 5mg
Storage

Shipped at 4°C. Store at -20°C for one year.
Purity

> 95%
Source

Synthetic
Forma appearance

Lyophilized powder
  • For research use only
  • Not for use in diagnostic procedures

€275,00 – €1.157,00 Tax excluded
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