GpTX-1 Toxin

Product overview
Catalog Number
PPH08-0488
Sequence
H-Asp-Cys-Leu-Gly-Phe-Met-Arg-Lys-Cys-Ile-Pro-Asp-Asn-Asp-Lys-Cys-Cys-Arg-Pro-Asn-Leu-Val-Cys-Ser-Arg-Thr-His-Lys-Trp-Cys-Lys-Tyr-Val-Phe-NH2
Target
Tarantula Spider Venom Peptide Antagonist; Possible Therapeutic Target for Pain Treatment 34 amino acid peptide with selective antagonist activity for Nav1.7 channel, A synthetic Tarantula Spider Venom peptide
Description
GpTx-1 is a 34-residue peptide with inhibitory cystine knot motif and contains 3 important residues near the C-terminus that are critical for potently blocking NaV1.7 channel, with IC50 value of 10 nM. The peptide toxin was originally isolated from the Grammostola porteri spider venom1,2. In addition, GpTx-1 demonstrates selectivity against other NaV subtypes including NaV1.4 and NaV1.5 channels. Tarantula Venom Peptide Antagonist; Possible Therapeutic Target for Pain Treatment; 34 amino acid peptide with selective antagonist activity for Nav1.7 channel
Category
Catalog peptides, Biologically Active Peptides
Product Properties
Quantity

1mg, 5mg
Storage

Shipped at 4°C. Store at -20°C for one year.
Purity

> 95%
Source

Synthetic
Forma appearance

Lyophilized powder
  • For research use only
  • Not for use in diagnostic procedures

€1.157,00 – €4.688,00 Tax excluded
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