HG1 Toxin

Product overview
Catalog Number
PPH08-0617
Sequence
GHHNRVNCLLPPKTGPCKGSFARYYFDIETGSCKAFIY_x000D_ GGCEGNSNNFSEKHHCEKRCRGFRKFGGK
Target
Inhibits currents with an IC50 of 6.2 nM (where 1 µM inhibits 80% of currents). Also has weak inhibitory activity against mKv1.1/KCNA1 (where 1 µM inhibits less than 50% of currents), hKv1.2/KCNA2 (where 1 µM inhibits less than 50% of currents), and hKCa2
Description
A Kunitz-type toxin specific for mKv1.3/KCNA3 potassium channel. Inhibits currents with an IC50 of 6.2 nM (where 1 µM inhibits 80% of currents). Also has weak inhibitory activity against mKv1.1/KCNA1 (where 1 µM inhibits less than 50% of currents), hKv1.2/KCNA2 (where 1 µM inhibits less than 50% of currents), and hKCa2.3/KCNN3. This toxin shas potential for diagnosing and treating Kv1.3-mediated autoimmune diseases
Category
Product Properties
Quantity

50µg, 100µg, 500µg, 2500µg

Storage

Shipped at 4°C. Store at -20°C for one year.

Purity

> 95%

Source

Synthetic

Forma appearance

Lyophilized powder

  • For research use only
  • Not for use in diagnostic procedures

475,003.480,00 Tax excluded

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