Kisspeptin-10 (Human) / Metastin (Human, 45-54) (0.5 mg vial)

Product overview
Catalog Number
PPH08-0656
Sequence
Tyr-Asn-Trp-Asn-Ser-Phe-Gly-Leu-Arg-Phe-NH2
Target
Endogenous Ligand for G-Protein Coupled Receptor hOT7T175, Stimulator of LH-HR/GnRH and gonadotropin secretion
Description
Kisspeptin was originally identified as a human metastasis suppressor gene that has the ability to suppress melanoma and breast cancer metastasis. Kisspeptin-GPR54 signaling has an important role in initiating secretion of gonadotropin-releasing hormone (GnRH) at puberty from the anterior pituitary. This peptide sequence is found in residues 45 to 54 of Metastin (also referred to as Kisspeptin-10). This peptide increases plasma concentrations of GH (Growth Hormone) and LH (Luteinizing Hormone) in prepubertal dairy heifers. This peptide is the minimal sequence needed to activate GPR54 signaling, which may function in negatively regulating CXCR4’s role in programming tumor metastasis. Specifically, Kisspeptin-10 inhibits signaling and chemotaxis induced by SDF-1. KiSS-1 Gene Product (Human, 112-121 Amide), KP-10 (Human) (M.W. 1302.4) C63H83N17O14 Synthetic Product. Endogenous Ligand for G-Protein Coupled Receptor hOT7T175
Category
Catalog peptides, Biologically Active Peptides
Product Properties
Quantity

1mg
Storage

Shipped at 4°C. Store at -20°C for one year.
Purity

> 95%
Source

Synthetic
Forma appearance

Lyophilized powder
Price

€77,00
  • For research use only
  • Not for use in diagnostic procedures

€77,00 Tax excluded
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