Leptin Human Recombinant
Product overview
- Catalog Number
- PPH08-0681
- Sequence
- The sequence of the first five N-terminal amino acids was determined and was found to be Ala-Val-Pro-Ile-Gln.
- Target
- Western Blot (WB), ELISA (EIA)
- Description
- Recombinant Human Leptin/OB stimulates cell proliferation in the BaF3 mouse pro-B cell line transfected with human Leptin R. The ED50for this effect is 0.4-2 ng/mL. Leptin is a protein product of the mouse obese gene. Mice with mutations in the obese gene that block the sythesis of Leptin have been found to be obese, diabetic and to have reduced activity, metabolism and body temperature. cDNA clones encoding Leptin have been isolated from human, simian, mouse and rat cells. Human Leptin shares approximately 84% sequence identity with the mouse protein. Human Leptin cDNA encodes a 167 amino acid residue protein with a 21 amino acid residue signal sequence that is cleaved to yield the 146 amino acid residue mature protein. The expression of Leptin mRNA has been shown to be restricted to adipose tissue. Western Blot (WB), ELISA (EIA)
Category
Product Properties
| Quantity | 1000µg, 5000µg |
|---|---|
| Storage | Shipped at 4°C. Store at -20°C for one year. |
| Purity | > 95% |
| Source | Synthetic |
| Forma appearance | Lyophilized powder |
- For research use only
- Not for use in diagnostic procedures
€110,00 – €430,00 Tax excluded
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