Linaclotide

Product overview
Catalog Number
PPH08-0675
Sequence
H-Cys-Cys-Glu-Tyr-Cys-Cys-Asn-Pro-Ala-Cys-Thr-Gly-Cys-Tyr-OH
Target
Agonist of Gaunylate Cyclase 2c
Description
Linaclotide is the first member of a novel class of drugs to be extensively evaluated for the treatment of chronic constipation (CC) and irritable bowel syndrome with constipation (IBS-C). Linaclotide was approved by the FDA for the treatment of chronic idiopathic constipation and irritable bowel syndrome with constipation in adults.196 It is a synthetic peptide analog of diarrheagenic bacterial enterotoxins and endogenous hormones guanylin and uroguanylin, which act as a potent guanylate cyclase C (GCC) receptor agonist. Trifluoroacetate Salt. Disulfide Bonds: Cys1-Cys6, Cys2-Cys10, Cys5-Cys13. Linzess; Constella. Agonist of Gaunylate Cyclase 2c.
Category
Catalog peptides, Biologically Active Peptides
Product Properties
Quantity

1mg, 25mg
Storage

Shipped at 4°C. Store at -20°C for one year.
Purity

> 95%
Source

Synthetic
Forma appearance

Lyophilized powder
  • For research use only
  • Not for use in diagnostic procedures

€649,00 – €2.655,00 Tax excluded
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