Muscarinic Toxin 7 (0.1mg vial)

Product overview
Catalog Number
PPH08-0726
Sequence
Leu-Thr-Cys-Val-Lys-Ser-Asn-Ser-Ile-Trp-Phe-Pro-Thr-Ser-Glu-Asp-Cys-Pro-Asp-Gly-Gln-Asn-Leu-Cys-Phe-Lys-Arg-Trp-Gln-Tyr-Ile-Ser-Pro-Arg-Met-Tyr-Asp-Phe-Thr-Arg-Gly-Cys-Ala-Ala-Thr-Cys-Pro-Lys-Ala-Glu-Tyr-Arg-Asp-Val-Ile-Asn-Cys-Cys-Gly-Thr-Asp-Lys-Cys-Asn
Target
Specific Ligand for Muscarinic Acetylcholine Receptor-1 (M1), A synthetic snake toxin peptide
Description
Muscarinic toxin 7 (MT7) is one member of a family of small peptides of 65 amino acid residues derived from the venom of African mamba snakes (Dendroaspis angusticeps), which mainly target M1-subtype of muscarinic receptor. Muscarinic toxins like the nicotinic toxins have the three-finger fold structure, characteristic of the large superfamily of toxins that act at cholinergic synapses. MT7 is likely to bind to the human M1 receptor in its dimer form with the tips of MT7 loops II and III contacting one hM1 protomer and the tip of loop I binds to the other protomer. MTX7, MT7, m1-toxin 1 (Green Mamba, Dendroaspis angusticeps) (Disulfide bonds between Cys3-Cys24, Cys17-Cys42, Cys46-Cys57, and Cys58-Cys63) (M.W. 7472.4) C322H484N90O98S9 Specific Ligand for Muscarinic Acetylcholine Receptor-1 (M1)
Category
Product Properties
Quantity

1mg

Storage

Shipped at 4°C. Store at -20°C for one year.

Purity

> 95%

Source

Synthetic

Forma appearance

Lyophilized powder

Price

€366,00

  • For research use only
  • Not for use in diagnostic procedures

366,00 Tax excluded

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