NAP Peptide

Product overview
Catalog Number
PPH08-0829
Sequence
H-Asn-Ala-Pro-Val-Ser-Ile-Pro-Gln-OH
Target
This octopeptide may have neuroprotective effects against schizophrenia-related impairment, toxicity associated with beta-amyloid and other compounds, stabilizing microtuble breakdown which may suggest therapeutic strategies for Parkinson's, Alzheimer's a
Description
NAP is an octapeptide derived from activity-dependent neuroprotective protein (ADNP); it exhibits neuroprotective, antioxidative, cognition enhancing, anti-aging, and antipsychotic activities. NAP increases levels of Bcl-2 and activates MAPK/ERK signaling in retinal cells of diabetic mice, preventing retinal apoptosis. NAP also increases expression of Nrf2, heme oxygenase-1 (HO-1), glutathione transferase, and superoxide dismutase 1 (SOD1) in vivo, protecting against oxidative stress and improving memory performance in the radial arm maze. NAP decreases phosphorylation of tau protein in animal models of amyotrophic lateral sclerosis (ALS), protecting spinal cord motor neurons and increasing life span. NAP shows some clinical benefit in the treatment of neurodegenerative diseases such as ALS and progressive supranuclear palsy (PSP). Additionally, this peptide also inhibits cognitive dysfunction in animal models of schizophrenia.Short Neuropeptide Fragment Derived from Activity-Dependent Neuroprotective Protein (ADNP); May Have Neuroprotective Effects Against Schizophrenia-Related Impairment, Toxicity Associated with Beta-Amyloid and Other Compounds, NAP peptide is a short neuropeptide fragment derived from Activity-Dependent Neuroprotective Protein (ADNP). C36H60N10O12. CAS # 211439-12-2. WM 824.94. L-Asparaginyl-L-alanyl-L-prolyl-L-valyl-L-seryl-L-isoleucyl-L-prolyl-L-glutamine. Davunetide.
Category
Product Properties
Quantity

5mg, 25mg

Storage

Shipped at 4°C. Store at -20°C for one year.

Purity

> 95%

Source

Synthetic

Forma appearance

Lyophilized powder

  • For research use only
  • Not for use in diagnostic procedures

80,00380,00 Tax excluded

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