PAMP (Human) (0.5 mg vial)

Product overview
Catalog Number
PPH08-0865
Sequence
Ala-Arg-Leu-Asp-Val-Ala-Ser-Glu-Phe-Arg-Lys-Lys-Trp-Asn-Lys-Trp-Ala-Leu-Ser-Arg-NH2
Target
Hypotensive Peptide
Description
Proadrenomedullin (1 – 20) (PAMP) was described as the gene related peptide of Adrenomedullin , both peptides are cleaved from the same precursor. In different test models PAMP seems to be significantly more potent than Adrenomedullin. In addition it was reported that PAMP also depressed basal aldosterone secretion and is expressed in human cancer cell lines. Different publications show that this peptide has different functions as a universal autocrine growth factor. Scientists from the University of Tokyo described effects on the growth of human neuroblastoma TGW cells by Proadrenomedullin N-terminal 20 peptide. This effect can be blocked by ω-conotoxin GIVA code 4161-v, which indicates a mechanism by inhibiting N-type Ca2+ channels.
Category
Product Properties
Quantity

1mg

Storage

Shipped at 4°C. Store at -20°C for one year.

Purity

> 95%

Source

Synthetic

Forma appearance

Lyophilized powder

Price

€248,00

  • For research use only
  • Not for use in diagnostic procedures

248,00 Tax excluded

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