PF 4
Product overview
- Catalog Number
- PPH08-0901
- Sequence
- EAEEDGDLQC LCVKTTSQVR PRHITSLEVI KAGPHCPTAQ LIATLKNGRK ICLDLQAPLY
- Target
- Platelet factor-4 is a 70-amino acid protein that is released from the alpha-granules of activated platelets and binds with high affinity to heparin. Its major physiologic role appears to be neutralization of heparin-like molecules on the endothelial surf
- Description
- Platelet factor 4 (PF4) is a small cytokine belonging to the CXC chemokine family that is also known as chemokine (C-X-C motif) ligand 4 (CXCL4) . This chemokine is released from alpha-granules of activated platelets during platelet aggregation, and promotes blood coagulation by moderating the effects of heparin-like molecules. Due to these roles, it is predicted to play a role in wound repair and inflammation. It is usually found in a complex with proteoglycan. Platelet Factor-4 Human (CXCL4), CXCL4, PF-4, PF4, Iroplact, Oncostatin-A, SCYB4, MGC138298. The sequence of the first four N-terminal amino acids was determined and was found to be Glu-Ala-Glu-Glu. Human CXCL4 although stable at 25C 1 week, should be stored desiccated below -18C. Please prevent freeze-thaw cycles. Human PF-4 a 7.8 kDa protein consisting of 70 amino acid residues. The CXCL4 protein was lyophilized in PBS buffer pH-7.4.
Category
Product Properties
| Quantity | 5mg, 20mg |
|---|---|
| Storage | Shipped at 4°C. Store at -20°C for one year. |
| Purity | > 95% |
| Source | Synthetic |
| Forma appearance | Lyophilized powder |
- For research use only
- Not for use in diagnostic procedures
€30,00 – €110,00 Tax excluded
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