Src Homology 2 Domain (Biotinylated)

Product overview
Catalog Number
PPH08-0970
Sequence
Biotinyl-ε-Aminocaproyl-Glu-Pro-Gln-Tyr(PO3H2)-Glu-Glu-Ile-Pro-Ile-Tyr-Leu-OH
Target
For SH2 Domain Ligand
Description
Src homology 2 (SH2) 2 domains are small modular protein domains that bind specifically to tyrosine-phosphorylated sites on proteins. In cell signaling, proteins that contain SH2 domains function to “read” post-translational marks that are “written” by activated tyrosine kinases and are “erased” by protein-tyrosine phosphatases (PTPs). Protein complexes mediated by SH2–phosphotyrosine (pTyr) interactions are critical for downstream signaling from a number of important tyrosine-phosphorylated proteins, including activated receptor tyrosine kinases such as the epidermal growth factor receptor (EGFR), and the proteins phosphorylated by receptor tyrosine kinases as well as by non-receptor cytoplasmic tyrosine kinases, such as Abl and Src. (Acetate Salt) (M.W. 1813.0) C82H122N15O27SP . For SH2 Domain Ligand
Category
Catalog peptides, Biologically Active Peptides
Product Properties
Quantity

1mg, 5mg
Storage

Shipped at 4°C. Store at -20°C for one year.
Purity

> 95%
Source

Synthetic
Forma appearance

Lyophilized powder
  • For research use only
  • Not for use in diagnostic procedures

€499,00 – €2.056,00 Tax excluded
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