Ubenimex (Bestatin)

Product overview
Catalog Number
PPH07-322
Sequence
[(2S,3R)-3-Amino-2-Hydroxy-4-Phenylbutanoyl]-L-Leucine
Target
An Inhibitor of Aminopeptidases, Leucine Aminopeptidase 3 (LAP3), and a Potent, Irreversible Inhibitor of Leukotriene A4 (LTA4) Hydrolase. Has antibacterial properties against P. gingivalis and F. nucleatum
Description
Ubenimex (INN), also known more commonly as bestatin, is a competitive, reversible protease inhibitor. It is an inhibitor of arginyl aminopeptidase (aminopeptidase B), leukotriene A4 hydrolase (a zinc metalloprotease that displays both epoxide hydrolase and aminopeptidase activities), alanyl aminopeptidase (aminopeptidase M/N), leucyl/cystinyl aminopeptidase (oxytocinase/vasopressinase), and membrane dipeptidase (leukotriene D4 hydrolase). It is being studied for use in the treatment of acute myelocytic leukemia and lymphedema. It is derived from Streptomyces olivoreticuli. Ubenimex has been found to inhibit the enzymatic degradation of oxytocin, vasopressin, enkephalins, and various other peptides and compounds. Hydrochloride. CAS 65391-42-6. Molecular Weight: 308.38 x 36.46
Category
Enzyme Inhibitors and Substrates, Catalog peptides
Product Properties
Quantity

25mg, 100mg
Storage

Shipped at 4°C. Store at -20°C for one year.
Purity

> 95%
Source

Synthetic
Forma appearance

Lyophilized powder
  • For research use only
  • Not for use in diagnostic procedures

€109,00 – €366,00 Tax excluded
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