Uroguanylin (Human)

Product overview
Catalog Number
PPH08-1028
Sequence
H-Asn-Asp-Asp-Cys-Glu-Leu-Cys-Val-Asn-Val-Ala-Cys-Thr-Gly-Cys-Leu-OH
Target
Intestinal peptide hormone | Regulator for electrolyte/fluid transport in the gastrointestinal epithelium
Description
Uroguanylin is a 16 amino acid peptide that is secreted by enterochromaffin cells in the duodenum and proximal small intestine. Guanylin acts as an agonist of the guanylyl cyclase receptor guanylate cyclase 2C (GC-C), and regulates electrolyte and water transport in intestinal and renal epithelia. In humans, the uroguanylin peptide is encoded by the GUCA2B gene. Uroguanylin may be involved in appetite and perceptions of 'fullness' after eating meals, as suggested by a study into mice.[Human uroguanylin is a 16 mer intestinal peptide with 2 disulfide bonds and acts as a potent guanylate Cylase C agonist. Uroguanylin shows a very high structural similarity to the heat resistant E.Coli Enterotoxin (Sta). Trifluoroacetate Salt. Disulfide Bonds: Cys4-Cys12 and Cys7-Cys15. [154525-25-4]
Category
Catalog peptides, Biologically Active Peptides
Product Properties
Quantity

1mg, 5mg
Storage

Shipped at 4°C. Store at -20°C for one year.
Purity

> 95%
Source

Synthetic
Forma appearance

Lyophilized powder
  • For research use only
  • Not for use in diagnostic procedures

€569,00 – €2.334,00 Tax excluded
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