Urotensin II (Rat) (0.5 mg vial)
Product overview
- Catalog Number
- PPH08-1025
- Sequence
- Pyr-His-Gly-Thr-Ala-Pro-Glu-Cys-Phe-Trp-Lys-Tyr-Cys-Ile[Pyr110]
- Target
- Urotensin II (Rat) is a potent Vasoconstrictor with negative inotropic effects.
- Description
- Urotensin II (U-II) is a disulfide-linked small peptide initially isolated from fish urophysis. Subsequently, the cDNA sequence encoding the human U-II precursor was determined, and the corresponding mRNA was found to exist predominantly in spinal cord [Proc. Natl. Acad. Sci. USA, 95, 15803 (1998)]. Human U-II, then, was revealed to be an agonist for the orphan receptor GPR14 and exerts a strong vasoconstricting activity in the isolated thoracic aorta of rat [Nature, 401, 282 (1999)]. The potency of vasoconstriction of U-II is an order of magnitude greater than that of endothelin-1, making human U-II the most potent mammalian vasoconstrictor identified so far. [Pyr110]-Prepro-Urotensin II (Rat, 110-123) (M.W. 1663.9) C77H102N18O20S2 . Synthetic Product (Disulfide bond between Cys8– Cys13). Urotensin II (Rat) is a potent Vasoconstrictor with negative inotropic effects.
Category
Product Properties
| Quantity | 1mg |
|---|---|
| Storage | Shipped at 4°C. Store at -20°C for one year. |
| Purity | > 95% |
| Source | Synthetic |
| Forma appearance | Lyophilized powder |
| Price | €237,00 |
- For research use only
- Not for use in diagnostic procedures
€237,00 Tax excluded
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