Urotensin II-Related Peptide (Human, Rat) (0.5 mg vial)
Product overview
- Catalog Number
- PPH08-1026
- Sequence
- Ala-Cys-Phe-Trp-Lys-Tyr-Cys-Val
- Target
- Potent Vasoconstrictor Endogenous Hypotensive Peptide
- Description
- UII-related peptide (URP), was discovered by monitoring UII-immunoreactivity in the rat brain, and its amino acid sequence was determined to be ACFWKYCV. cDNAs encoding rat, mouse, and human precursor proteins for URP were cloned and showed that the sequences of mouse and human URP peptides are identical to that for rat URP. URP was found to bind and activate the human or rat urotensin II receptors [GPR14, UT receptor (UTR)] and showed a hypotensive effect when administrated to anesthetized rats. The prepro-URP gene is expressed in several rat tissues, although with lower levels than the prepro-UII gene and, in the human, is expressed comparably to prepro-UII in several tissues except the spinal cord. These results suggest that URP is the endogenous and functional ligand for urotensin II receptor in the rat and mouse, and possibly in the human. ACFWKYCV. URP (human, mouse, rat), Urotensin IIB (human, mouse, rat), UIIB (human, mouse, rat) C₄₉H₆₄N₁₀O₁₀S₂. Relative Molecular Mass 1017.24. CAS 342878-90-4. Synthetic
Category
Product Properties
| Quantity | 1mg |
|---|---|
| Storage | Shipped at 4°C. Store at -20°C for one year. |
| Purity | > 95% |
| Source | Synthetic |
| Forma appearance | Lyophilized powder |
| Price | €141,00 |
- For research use only
- Not for use in diagnostic procedures
€141,00 Tax excluded
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