[Val5]-Angiotensin II (0.5 mg vial)
Product overview
- Catalog Number
- PPH08-1035
- Sequence
- Asp-Arg-Val-Tyr-Val-His-Pro-Phe
- Target
- The biological activity of these peptides is examined by the Division of Pharmacology, Peptide Institute, Inc.
- Description
- Angiotensin II (AT II) is a peptide produced from AT I by angiotensin-converting-enzyme (ACE). AT II binds the AT II type 1 (AT1) receptor, stimulating GPCRs in vascular smooth muscle cells and increasing intracellular Ca2+ levels; this results in contraction and vasoconstriction, increasing blood pressure. AT II also acts at the Na+/H+ exchanger in the proximal tubules of the kidney. Here, AT II increases reabsorption of Na+ and HCO3- and excretion of H+, increasing blood volume and pH and further increasing blood pressure. (M.W. 1032.2; 60.05; 72.06) C49H69N13O12; CH3COOH; 4H2O [5649-07-0]
Category
Product Properties
| Quantity | 5mg |
|---|---|
| Storage | Shipped at 4°C. Store at -20°C for one year. |
| Purity | > 95% |
| Source | Synthetic |
| Forma appearance | Lyophilized powder |
| Price | €19,00 |
- For research use only
- Not for use in diagnostic procedures
€19,00 Tax excluded
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