VIP (Human, Porcine) (0.5 mg vial)

Product overview

Sequence: His-Ser-Asp-Ala-Val-Phe-Thr-Asp-Asn-Tyr-Thr-Arg-Leu-Arg- Lys-Gln-Met-Ala-Val-Lys-Lys-Tyr-Leu-Asn-Ser-Ile-Leu-Asn-NH2

Description: Vasoactive Intestinal Peptide, VIP. The 28-amino acid neuropeptide VIP (Vasoactive Intestinal Peptide) is a neurotransmitter and a neuromodulator. VIP is broadly distributed in the peripheral and central nervous systems. It has an amino acid sequence identity of 68% with pituitary adenylate cyclase-activating polypeptide (PACAP). VIP and PACAP inhibit TNF-a, IL-1ß, IL-6, and NO production by lipopolysaccharide (LPS)-activated microglia. Both regulate the production of proinflammatory factors at a transcriptional level by inhibiting p65 nuclear translocation and nuclear factor-kB-DNA binding. As well, VIP relaxes the smooth muscle of the respiratory, gastrointestinal and reproductive tracts, stimulates exocrine and endocrine secretion, increases the survival time of neurons, and promotes the proliferation of untransformed and cancer cells. This sandwich kit is for the accurate quantitative detection of human Ubiquitin Specific Peptidase 18 (also known as USP18) in serum, plasma, cell culture supernates, cell lysates, tissue homogenates. VIP causes vasodilation, lowers arterial blood pressure, stimulates myocardial contractility, increases glycogenolysis and relaxes the smooth muscle of trachea, stomach and gall bladder. Molecular Weight: 19,082 Da

Quantity	1mg
Storage	Shipped at 4°C. Store at -20°C for one year.
Purity	> 95%
Source	Synthetic
Forma appearance	Lyophilized powder
Price	€403,00

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